Core Outcome Measures in Effectiveness Trials

Who we are

Paula Williamson, Doug Altman, Jane Blazeby and Mike Clarke form the Management Group for the COMET Initiative and have been working together as such since January 2010. Sean Tunis subsequently joined the Management Group in 2015. Elizabeth Gargon is the COMET Project Coordinator.

Doug Altman

Doug Altman
Doug Altman has been director of the Centre for Statistics in Medicine in Oxford since its inception in 1995. He has published over 400 peer reviewed articles, many aimed at clarifying statistical ideas for medical researchers. He is author of Practical Statistics for Medical Research. His varied research interests include the use and abuse of statistics in medical research, studies of prognosis, regression modelling, systematic reviews and meta-analysis, randomised trials, and studies of medical measurement. Doug is senior statistical editor at the BMJ and co-editor-in-chief of Trials. He is actively involved in developing guidelines for reporting research, including CONSORT, STROBE, and PRISMA, and in 2006 founded the EQUATOR Network which seeks to improve the quality of scientific publications by promoting transparent and accurate reporting of health research.
 

 

Jane Blazeby

Jane Blazeby
Jane Blazeby is Professor of Surgery at the University of Bristol and an Honorary Consultant Surgeon at University Hospitals Bristol NHS Foundation Trust. She is Director of the MRC ConDuCT Hub (Collaboration and Innovation for Difficult and Complex Randomised Controlled Trials) for trials methodology research. ConDucT focuses on several themes including developing methods for integrating clinical and patient reported outcomes to influence clinical decision-making.
 

 

Mike Clarke

Mike Clarke
Professor Mike Clarke is Chair of Research Methodology at Queen’s University in Belfast and Director of the all-Ireland Hub for Trials Methodology Research, since March 2011. He was Director of the UK Cochrane Centre from 2002 until then and has spent more than twenty years working on systematic reviews and large randomised trials in a range of areas. He has a strong interest in increasing capacity for the conduct of randomised trials and systematic reviews, and in improving accessibility to their findings, in particular in low and middle income countries. This includes his work on Evidence Aid, to make it easier for people and organisations planning for and responding to natural disasters to make well informed decisions about health care and other areas.
 

 

Paula Williamson

Paula Williamson
Paula Williamson is Professor of Medical Statistics and Director of the Clinical Trials Research Centre (CTRC) at the University of Liverpool. She is an Associate Director of the NIHR Medicines for Children Research Network, and Director of the MCRN Clinical Trials Unit. In 2008 she led a successful bid to create the MRC North West Hub for Trials Methodology Research (NWHTMR), focussing on three themes (early phase trial design and analysis, later phase trial design and analysis, patients’ perspectives), and developing methods for application across key clinical areas including paediatrics, drug safety, cancer and epilepsy.
 

 

Elizabeth Gargon

Elizabeth Gargon
Elizabeth Gargon obtained a First class Bachelor of Science Degree in Psychology and Health Science from The University of Liverpool in 2007. After graduating, she went on to work for a patient reported outcomes (PRO) consultancy specialising in the development and use of PRO endpoints in clinical trials. In October 2009, Elizabeth joined the University of Liverpool as a research assistant for a vital research programme funded by the National Institute of Health Research (NIHR), and worked in collaboration with Alder Hey Children’s NHS Foundation Trust. Elizabeth is the Project Coordinator for the COMET Initiative.
 

 

Sean Tunis

Sean Tunis
Sean Tunis is President and Chief Executive Officer of the Center for Medical Technology Policy (CMTP) in Baltimore, Maryland. CMTP is an independent, non-profit organization that provides a neutral platform for multi-stakeholder collaborations that promote high value innovation by improving the quality, relevance, and efficiency of clinical research. Through September of 2005, Dr. Tunis was the Director of the Office of Clinical Standards and Quality and Chief Medical Officer at the Centers for Medicare and Medicaid Services (CMS). He also served as the Director of the Health Program at the Congressional Office of Technology Assessment and as a health policy advisor to the U.S. Senate Committee on Labor and Human Resources. He received a B.S. degree in Biology and History of Science from the Cornell University School of Agriculture, and a medical degree and masters in Health Services Research from the Stanford University School of Medicine. Dr. Tunis did his residency training at UCLA and the University of Maryland in Emergency Medicine and Internal Medicine.Dr. Tunis serves as Vice-President of Health Technology Assessment International, a member of the Health Sciences Policy Council for ISPOR and on several other public and private governing and advisory boards.
 

The site uses cookies, some may have been set already. Please refer to our privacy policy & cookie usage statement.
If you continue to use the site we'll assume you're happy to accept the cookies.