Core Outcome Measures in Effectiveness Trials

COS Uptake and Endorsement

It is important to assess the uptake and use of COS in clinical trials, and other research, in order to avoid the development of these COS contributing to the research waste which their development aims to reduce. Assessing uptake can also highlight the benefits of measuring and reporting COS in trials while allowing review and feedback to ensure ongoing relevance, and removal of barriers and facilitators to uptake. A collection of Podcasts highlight the importance of the development and use of COS to people from a range of different backgrounds.

The following organisations actively endorse the use of COS and the COMET database.


Trial Funders

Trial Registries

Regulatory Authorities

Systematic Review Groups

Clinical Guideline Development Groups

Journal Editors


COS Collaborative Groups

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