Core Outcome Measures in Effectiveness Trials

Outcome Reporting in Randomized Trials for Shoulder Disorders: Literature Review to Inform the Development of a Core Outcome Set

General Information

Abstract:
OBJECTIVE: To explore the outcome domains and measurement instruments reported across randomized trials of any interventions for various shoulder disorders. METHODS: We searched for shoulder trials included in Cochrane reviews published up to Issue 10, 2015, or indexed in PubMed between 2006 and 2015. Trials were eligible for inclusion if they focused on any intervention for rotator cuff disease, adhesive capsulitis, shoulder instability, glenohumeral or acromioclavicular osteoarthritis, shoulder dislocation, proximal humeral or humeral head fractures, or unspecified shoulder pain. Two authors independently selected trials for inclusion and extracted information on the domains and measurement instruments reported, with consensus discussion among all authors where required. RESULTS: We included 409 trials, published between 1954 and 2015. Across the trials, we identified 319 different instruments that were classified into 32 domains. Most trials reported a measure of pain (90%), range of motion (78%), and physical function (71%). The recording of adverse events was reported in only 31% of the trials. Muscle strength was reported in 44% of the trials and imaging outcomes in 21%. Other patient-reported outcome measures, such as global assessment of treatment success, health-related quality of life, work ability, and psychological functioning, were each reported in less than or equal to15% of the trials. Most of the domains were reported at similar frequencies across different shoulder disorders. CONCLUSION: The domains and measurement instruments reported were widely diverse. Our results provide a foundation for the development of a core outcome set for use in future trials across all shoulder disorders.

Authors:
Page, M. J. Huang, H. Verhagen, A. P. Gagnier, J. J. Buchbinder, R.

Publication

Journal:
Arthritis Care Res (Hoboken)
Volume:
70
Issue:
2
Pages:
252 - 259
Year:
2018
DOI:
Further Study Information

Date:
Not stated
Funding source(s):
Supported by a Patient-Centered Outcomes Research Institute Eugene Washington Engagement Award (2072). Dr. Page is supported by an Australian National Health and Medical Research Council Early Career Fellowship (1088535). Dr. Buchbinder is supported by an Australian National Health and Medical Research Council Senior Principal Research Fellowship.

Health Area

Disease Category
Orthopaedics & trauma

Disease Name
Shoulder disorders

Target Population

Age Range
-

Sex
Either


Nature / type of Intervention
Any

Method(s)

Systematic review

Stakeholders Involved

None

Study Type

Systematic review of outcomes measured in trials

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