Core Outcome Measures in Effectiveness Trials

A modified Delphi and cross-sectional survey to facilitate selection of optimal outcomes and measures for a systematic review on geriatrician-led care models

General Information

Abstract:
OBJECTIVE: To identify relevant outcomes and measures to inform a systematic review (SR) on the comparative effectiveness of geriatrician-led care models. STUDY DESIGN AND SETTING: In the modified Delphi to select outcomes for inclusion in the SR, knowledge users (KU) from Ontario, Alberta and Saskatchewan rated outcome importance using a Likert scale. A survey was then completed by geriatricians to determine optimal measures for selected outcomes. Findings were analyzed using frequencies, means, and standard deviations (SD). RESULTS: 33 KUs (patients, caregivers, policy makers and geriatricians) rated 27 outcomes in round 1 of the modified Delphi. Top-rated outcomes included: function (mean 6.85 +/- SD 0.36), cognition (6.47+/- SD 0.72), and quality of life (6.38+/- SD 0.91). 23 KUs participated in round 2 and rated 24 outcomes. Top-rated outcomes in round 2 were: function (6.87+/- SD 0.34), quality of life (6.45+/- SD 1.10) and cognition (6.43+/- SD 0.73). The survey was completed by 22 geriatricians and the highest ranked measures were: Activities of Daily Living (function), Mini Mental State Exam (cognition) and the Medical Outcomes Study SF-36 (quality of life). CONCLUSION: We identified the most relevant outcomes and measures for patients, caregivers, policymakers and geriatricians, allowing us to tailor the SR to KU needs.

Authors:
Soobiah, C. Manley, G. Marr, S. Moore, A. PausJenssen, E. Teare, S. Hamid, J. Tricco, A. C. Straus, S.

Publication

Journal:
Journal of Clinical Epidemiology
Volume:
Issue:
Pages:
-
Year:
2019
DOI:
Further Study Information

Date:
Not stated
Funding source(s):
Strategy for Patient Orien ted Research (SPOR) Knowledge 72 Synthesis grant in Primary and Integrated Health Ca re Innovation (PHICI).

Health Area

Disease Category
Health care of older people

Disease Name
N/A

Target Population

Age Range
65 - 120

Sex
Either


Nature / type of Intervention
Any

Method(s)

Delphi process
Literature review
Survey

In the modified Delphi to select outcomes for inclusion in the SR, knowledge users (KU) from Ontario, Alberta and Saskatchewan rated outcome importance using a Likert scale. A survey was then completed by geriatricians to determine optimal measures for selected outcomes. Findings were analyzed using frequencies, means, and standard deviations (SD).


Stakeholders Involved

Clinical experts
Consumers (caregivers)
Consumers (patients)
Policy makers

Study Type

Recommendations made for systematic reviews
Recommended outcome measures (measurement)

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