Core Outcome Measures in Effectiveness Trials

Outcome assessment for Brachial Plexus birth injury. Results from the iPluto world-wide consensus survey

General Information

There is no consensus regarding strategies to optimally treat children with a brachial plexus birth injury (BPBI). Comparison of outcome data presented by different centers is impossible due to the use of (1) many different outcome measures to evaluate results; (2) different follow-up periods after interventions; and (3) different patient ages at the time of assessment. The goal of iPluto (international PLexus oUtcome sTudy grOup) was to define a standardized dataset which should be minimally collected to evaluate upper limb function in children with BPBI. This dataset must enable comparison of the treatment results of different centers if prospectively used. Three rounds of internet surveys were used to reach consensus on the dataset. A Delphi-derived technique was applied using a nine point Likert scale. Consensus was defined as having attained a rating of 7/8/9 by > = 75% of the participants. A total of 59 participants from five continents participated in the Second and Third Rounds of the survey. Consensus was reached regarding four elements: (1) evaluation should take place at the age of 1/3/5/7 years; range of motion in degrees should be measured for (2) passive joint movement; (3) active range of motion; and (4) the Mallet score should be determined. Consensus on how to asses and report outcome for BPBI was only reached on motor items from the "Body Function and Structure" domain. Consensus regarding additional ICF domains to obtain a more elaborate set of outcome items, should be addressed in future research. (c) 2018 The Authors. Journal of Orthopaedic Research(R) Published by Wiley Periodicals, Inc. on behalf of the Orthopaedic Research Society. J Orthop Res 36:2533-2541, 2018.

Pondaag, W. Malessy, M. J. A.


J Orthop Res
2533 - 2541
Further Study Information

Not stated
Funding source(s):

Health Area

Disease Category
Orthopaedics & trauma

Disease Name
Brachial plexus birth injury (BPBI)

Target Population

Age Range
0 - 18


Nature / type of Intervention


Delphi process

Stakeholders Involved

Clinical experts

Study Type

COS for clinical trials or clinical research
COS for practice
Minimum dataset
Recommended outcome measures (measurement)

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