Development of a core outcome data set based on consensus standardized (COD Dementia) to assess mild to moderate dementia with MOCA and laboratory biomarkers in Nursing Home
Method: The CBA database has been developed by a dedicated working group using Delphi process. It contain records on Cognitive functioning, Functioning of Activities of daily living, Neuropsychiatric symptoms and behaviours, Quality of life and Biomarkers. This work is required to identify the core variables for measurement.
Results: Between 2015 and 2016, 670 geriatric patients were enrolled at six Italian Nursing Home. Among these patients, 41% were men and 59% were women (mean age 80 years) and SOSIA form 3 was the most frequent classification system (59%) followed by 5 (21%), 7 (11%) and 1 (9%).
The SOSIA classification is based on motor skills, the ability cognitive/behavior and comorbidity.
The average score at MOCA, adjusted for age and education, amounted to 21.0, in MMSE is 19.0. Cognitive impairment was observed in 81.3% of patients with MOCA <26.
Multivariate analysis has determined that the identification of SOSIA form is strongly associated with the MOCA score correlated with the form 5 (p=0.02), 7 (p=0.01), comorbidities (p=0.001), using the "Cumulative Illness Rating Scale=4" and the "Barthel Index=100" (p<0.001).
The MMSE score correlates with the form 3 (p=0.01) and 1 (p=0.02).
Conclusion: COD Dementia enables the creation of databases that can be used to govern the provision of long-term care with SOSIA classification form, neurological tests across different health system, to answer relevant research questions and to compare characteristics of future trials.
and University of Milan Bicocca, Milan, Italy
Development CBA database using Delphi process.
Geriatric patients with SOSIA classification