The use of core outcome sets reduces heterogeneity in the reporting of outcomes in clinical trials, increasing the value and significance of research. This paper first introduces and interprets “core outcome sets for myocardial infarction (COS-MI) in clinical trials of traditional Chinese medicine and Western medicine”, in order to help Chinese researchers better understand and use it. Second, this study surveyed the use of COS-MI in MI related clinical trials from January 1, 2023 to June 1, 2024, showing that 91% (10/11) of the 35 acute myocardial infarction clinical studies included reported core outcomes, and the median percentage of using core outcome sets was only 36% (4/11). As the publication time of the core outcome set is close to the literature search time, the understanding of domestic researchers about it is still unclear. Further research is needed to explore the application of core outcome sets for myocardial infarction in clinical trials of traditional Chinese medicine and Western medicine, providing a reference for its update and improvement.
CHEN Zhuo, WAN Siqi, GUAN Zhiyue, ZHANG Xinyi, LIU Shuling, WANG Wenhui, QIU Ruijin, SHANG Hongcai
Disease Category: Heart & circulation
Disease Name: Myocardial infarction
Age Range: Unknown
Sex: Either
Nature of Intervention: Any, Traditional Chinese Medicine
- None
- COS uptake study
- Systematic review
Three Chinese databases (the China National Knowledge Infrastructure, SinoMed, and Wanfang Database) and three English databases (PubMed, the Cochrane Library, and Web of Science) will be searched. Registries of pre-clinical research, clinical trials, SR, and CPGs will also be searched.