A core outcome set (COS) is an agreed minimum set of outcomes that should be reported in all clinical trials in specific areas of health care. The use of COS can reduce the heterogeneity of outcomes reporting in different trials and enhance evidence synthesis in systematic review/meta-analysis by including more studies with the same outcome. It can also enhance the value of trials and reduce cost waste to some extent. Recently, Core Outcome Measures in Effectiveness Trials (COMET) initiative has developed the COMET handbook (version 1.0). This handbook discussed the problems of COS research and made some recommendations. This paper interprets the COMET handbook (version 1.0)and analyses its insight on the construction of TCM clinical research COS, combined with the characteristics of TCM clinical research, in order to provide a reference for related researchers.
ContributorsQIU Ruijin1, LI Min1, HAN Songjie1, HE Tianmai1, HUANG Ya1, CHEN Jing2, SHANG Hongcai1
1. Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of ChineseMedicine, Beijing, 100700, P.R.China2. Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, P.R.ChinaCorresponding author: CHEN Jing, Email: cjshcyc@126.com; SHANG Hongcai, Email: shanghongcai@foxmail.com
Disease Category: Other
Disease Name: N/A
Age Range: Unknown
Sex:
Nature of Intervention:
- COS methods research
This paper interprets the COMET handbook (version 1.0)and analyses its insight on the construction of TCM clinical research COS, combined with the characteristics of TCM clinical research, in order to provide a reference for related researchers.