Core outcome set for research on snakebite management in South Asia

Snakebite is a public health problem in many countries in South Asia, Africa and Latin America. In 2020, we published an overview of systematic reviews on snakebite management in PloS NTDs in which highlighting the limitations of non-standardized measurement and reporting of outcomes. There is no COS for snakebite registered in the COMET register for database of ongoing COS. The current study fills this gap by developing a Core Outcome Set of outcomes that should be minimally measured for research on snakebite management in the South Asian region.

Contributors

Soumyadeep Bhaumik & Jagnoor Jagnoor (1,2),

Jagnoor Jagnoor is the supervisor of Soumyadeep Bhaumik, PhD student leading the work.

Collaborators : Paula R Williamson (3), Mike Clarke (4), Sanjib Kumar Sharma (5)

Affiliations
1. The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia,
2. The George Institute for Global Health, New Delhi, India
3. Department of Biostatistics, University of Liverpool, Liverpool, UK
4. Northern Ireland Clinical Trials Unit and Methodology Hub, Centre for Public Health, Queen's University Belfast, Belfast, UK.
5. B.P. Koirala Institute of Health Sciences, Dharan, Nepal

Further Study Information

Current Stage: Completed – pending publication
Date: May 2021 - May 2022
Funding source(s): The study does not have any specific external funding. Soumyadeep Bhaumik is supported by the University International Postgraduate Award (UIPA) by University of New South Wales (UNSW), Sydney, Australia.

Health Area

Disease Category: Public health

Disease Name: Snakebite

Target Population

Age Range: 0 - 120

Sex: Either

Nature of Intervention: Any

Stakeholders Involved

- Clinical experts
- Consumers (caregivers)
- Consumers (patients)
- Governmental agencies
- Journal editors
- Methodologists
- Patient/ support group representatives
- Researchers
- Service providers

Study Type

- COS for clinical trials or clinical research

Method(s)

- Consensus meeting
- Delphi process
- Semi structured discussion
- Systematic review

The COS development process will be conducted in three phases. In phase 1, a global systematic review of outcomes will be conducted. In Phase 2, the initial list of outcomes identified, will be ranked in two rounds of Delphi survey and the COS adopted in an online consensus meeting. In Phase 3, a structured online workshop will be conducted for developing consensus recommendations for outcome measurements.

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