Developing a core outcome set for dental antibiotic stewardship

Antibiotic stewardship aims to ensure sustainable access to effective treatment of bacterial infections for all who need it by minimising unnecessary and inappropriate prescribing. Dentistry is responsible for an estimated 10% of antibiotics across healthcare worldwide, with up to 80% inappropriate. This study aims to develop international consensus on a set of meaningful core outcomes for dental antibiotic stewardship (COS-DAB) in research and routine clinical practice.


Principal investigator - Dr Wendy Thompson, University of Manchester

Further Study Information

Current Stage: Ongoing
Date: April 2021 - December 2021
Funding source(s): FDI World Dental Federation

Health Area

Disease Category: Dentistry & oral health

Disease Name: Antibiotic resistance

Target Population

Age Range: 0 - 120

Sex: Either

Nature of Intervention: Drug

Stakeholders Involved

- Charities
- Clinical experts
- Consumers (patients)
- Patient/ support group representatives
- Researchers
- Service providers
- Service users

Study Type

- COS for clinical trials or clinical research
- COS for practice


- Delphi process

Stage 1 - A long list of outcomes will be developed by the study steering group based on existing systematic reviews and core outcome sets.

Stage 2 - a Delphi process with experts by experience of antibiotics, clinical and academic experts.

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