Developing a core outcome set for urticaria

Objective: This study aimed to establish a COS for urticaria treatment in clinical trials.

Methods: According to the COMET handbook, we will first conduct a systematic review of the clinical research on urticaria to extract outcome indicators and construct a questionnaire. Next, we will organize a group of clinicians, nurses, patients, researchers, etc, to conduct in-depth interviews, and determine the core indicator set of urticaria through two rounds of anonymous Delphi questionnaire surveys and two rounds of consensus meetings.

Summarizing: This study hopes to provide clear guidance on which results should be measured in clinical trials for patients with urticaria,and hopes to help improve the health and well-being of these patients.



Contributors

Jianhong Li and Ruijin Qiu are the principal investigators.

Contributors: Jiacheng Gao.
Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine.


Further Study Information

Current Stage: Ongoing
Date: January 2025 - June 2027
Funding source(s): None


Health Area

Disease Category: Skin

Disease Name: Urticaria

Target Population

Age Range: 18 - 65

Sex: Either

Nature of Intervention: Any

Stakeholders Involved

- Clinical experts
- Conference participants
- Consumers (patients)
- Epidemiologists
- Ethicists
- Methodologists
- Patient/ support group representatives
- Researchers

Study Type

- COS for clinical trials or clinical research
- COS for practice

Method(s)

- Consensus conference
- Delphi process
- Literature review
- Survey
- Systematic review

According to the COMET handbook, we will first conduct a systematic review of the clinical research on urticaria to extract outcome indicators and construct a questionnaire. Next, we will organize a group of clinicians, nurses, patients, researchers, etc, to conduct in-depth interviews, and determine the core indicator set of urticaria through two rounds of anonymous Delphi questionnaire surveys and two rounds of consensus meetings.

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